Peptide Database

Peptide NameBeta-defensin 115 (Beta-defensin 15) (DEFB-15) (Defensin; beta 115)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC444H725N125O127S7

DescriptionStandard

        MLPDHFSPLSGDIKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKDKLSHIHDQKETSELYI
    

Molecular Weight10070.72 Da

Isoelectric Point (pI)8.77

Net Charge (pH 7.0)3.80

Net Charge (pH 7.4) 3.26

Charge Density (pH 7.0) 0.0432

GRAVY Index-0.41

Hydrophobic Moment 0.72

Boman Index-0.10

Instability Index43.86

Aliphatic Index 89.66

Aromaticity 0.0568

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4062.63

LogP -34.76

H-bond Donors 148.0

H-bond Acceptors 142.0

Rotatable Bonds 344.0

Heavy Atoms 703.0

Ring Count 14.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390926 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic