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MYP_090935
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Basic Information
VT18-CAKKLV (VT18 peptide derivative)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C99H139N21O21S2
Standard
Sequence
VYPFCWGGAYAFCKAKLV
Physicochemical Analysis
2023.42 Da
8.82
1.71
1.46
0.0950
0.81
0.25
0.41
40.78
70.56
0.2778
8480.00
8605.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
657.52
-0.95
25.0
25.0
58.0
143.0
7.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0179339 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PMID29277569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29277569/
RECORD: Rec_0185777 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-13
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus pneumoniae ATCC 700677
49 μg/mL
MIC
PMID29277569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29277569/
RECORD: Rec_0196321 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus pneumoniae ATCC 49619
90 μg/mL
MIC
PMID29277569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29277569/
RECORD: Rec_0215313 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
5-13
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Streptococcus pneumoniae ATCC 700677
49 μg/mL
MIC
PMID29277569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29277569/
RECORD: Rec_0251140 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-13
Bio-Activity Profile
Hemolytic
Human RBC
500 μg/mL
Hemolysis
PMID29277569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29277569/
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