Peptide Database

Peptide NamedltD signal peptide

Function Ontology

Annotation / Sequence feature ▸ Signal peptide

Biotechnology / Production and expression ▸ Secretory enzyme production ▸ Cutinase secretion

Biotechnology / Production and expression ▸ Secretory expression optimization

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC116H182N26O22S

DescriptionStandard

        MKKRFFGPIILAFILFAGAIA
    

Molecular Weight2324.91 Da

Isoelectric Point (pI)11.17

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 2.28

Charge Density (pH 7.0) 0.1190

GRAVY Index1.49

Hydrophobic Moment 0.49

Boman Index0.53

Instability Index39.35

Aliphatic Index 130.48

Aromaticity 0.1905

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 750.47

LogP 0.46

H-bond Donors 26.0

H-bond Acceptors 26.0

Rotatable Bonds 75.0

Heavy Atoms 165.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0190592 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus subtilis [Bacterium]

FamilySec signal peptide

Tax ID1423

Structure & Mods

Configlinear signal peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Protein secretion signal peptide Secretory expression optimization Cutinase secretion

TargetBacillus subtilis TEB1030

MethodSecretion phenotype assay

PaperBrockmeier U, Caspers M, Freudl R, et al. Systematic screening of all signal peptides from Bacillus subtilis: A powerful strategy in optimizing heterologous protein secretion in gram-positive bacteria[J]. Journal of Molecular Biology, 2006, 362(3): 393-402. PMID16930615 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16930615/