Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC447H720N136O140S8

DescriptionStandard

        MRTLTILAAILLFALLAQAKSLQETADDAATQEQPGEDDQDLAVSFEENGLSTLRPSGSQARTKCHCRIRRCNWYESNFGPCIIMGQRGRFCCR
    

Molecular Weight10495.85 Da

Isoelectric Point (pI)6.54

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.33

Hydrophobic Moment 0.53

Boman Index-0.08

Instability Index42.91

Aliphatic Index 75.96

Aromaticity 0.0638

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4501.05

LogP -52.05

H-bond Donors 163.0

H-bond Acceptors 149.0

Rotatable Bonds 352.0

Heavy Atoms 731.0

Ring Count 11.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423228 VERIFIED: NO

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyDefensin

Tax ID9531

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence