Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length152 amino acids

Chemical FormulaC767H1173N197O231S11

DescriptionStandard

        MNLLMLTFMICGLLNLVTKAGWFVERCWKNGVGHCRKRCLHLERYKLLCMNKLSCCIPLSSDDPYTPWPIRPTFGEDVTFGFGTHDGFPFSPVSGFDDEVTIKTTKTQETTVTGTTASERDSTQTLTTIPQSVEGTTFSHEPETADLYKYWD
    

Molecular Weight17202.42 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-4.19

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0276

GRAVY Index-0.29

Hydrophobic Moment 0.58

Boman Index0.04

Instability Index34.44

Aliphatic Index 65.99

Aromaticity 0.1118

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6816.83

LogP -67.18

H-bond Donors 245.0

H-bond Acceptors 242.0

Rotatable Bonds 550.0

Heavy Atoms 1206.0

Ring Count 34.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117462 VERIFIED: NO

Provenance & Taxonomy

OrganismTursiops truncatus [Animal]

FamilyDefensin

Tax ID9739

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence