Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC33H41N5O8

DescriptionStandard

        YKYY
    

Molecular Weight635.71 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.1890

GRAVY Index-1.95

Hydrophobic Moment 0.46

Boman Index-0.18

Instability Index38.35

Aliphatic Index 0.00

Aromaticity 0.7500

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 237.33

LogP 0.83

H-bond Donors 9.0

H-bond Acceptors 9.0

Rotatable Bonds 17.0

Heavy Atoms 46.0

Ring Count 3.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424171 VERIFIED: YES

Provenance & Taxonomy

OrganismUndaria pinnatifida [Protist]

FamilyACE inhibitory peptide

Tax ID74381

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory Antihypertensive Enzyme-inhibitory

TargetAngiotensin-converting enzyme

Activity64.2 μM

MethodIC50

PaperIdentification of an antihypertensive peptide from peptic digest of wakame (Undaria pinnatifida) | Review on the angiotensin-I-converting enzyme (ACE) inhibitor peptides from marine proteins | Vegetable foods: a cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities | Isolation and characterization of peptides with antihypertensive activity in foodstuffs

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