Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length549 amino acids

Chemical FormulaC2739H4318N720O749S22

DescriptionStandard

        MAPHPPKPSGPISGHLWGCLLPPLPPLPRFLPPFYILLVSISPAGSFRAPWLPSKASRFGGSGRQNMAREPDKASMRATLVVLATLGTAVIATTNPGVVARITQKGLDYACQQGMTVLRKELEKITIPTFSGTFEIKHLGEGHYSFYSMAIRGFQILGSQIELVPSEGLHLFISNASVKISGKWKARKNFIKTSGNFDLSVEGVSISAGLKPGFDPASGHCTVTCSACRNHIESVRVHISGSGLGWLIKLFHKKMESALQKMMNKKICQVVTNSVSSKLQPYLETLPVKTQIDNVAGIDYSLVAPPTTTTDNLDGQLKGEFFRWNQRSPPPFAPPPLAFPGDHDRMVYLGISDYFFNTAGFVYQQAGALNLTVTDNMIPKKSKFRLTTNFFGILIPQVATMFPNMEVQLVFWASSPPHLTMNPASLVFTPTLDTQAFAVLQNSSLAPLFVLRLTMNISVTVGATLDRLVGQLELNKLLLELKHSDVGPFSVGVLQAVMSYVVPIAVIPKVNERLQKGFPLPMPAKLQAFNLVLRSHQNFLLLGADVRYS
    

Molecular Weight60023.39 Da

Isoelectric Point (pI)9.67

Net Charge (pH 7.0)19.60

Net Charge (pH 7.4) 18.54

Charge Density (pH 7.0) 0.0357

GRAVY Index0.10

Hydrophobic Moment 0.65

Boman Index0.15

Instability Index43.49

Aliphatic Index 94.46

Aromaticity 0.0893

Extinction Coeff. Reduced 49390.00

Extinction Coeff. Oxidized 49765.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0361774 VERIFIED: NO

Provenance & Taxonomy

OrganismSuricata suricatta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria