Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length458 amino acids

Chemical FormulaC2282H3650N600O637S16

DescriptionStandard

        MGVQSLAVACGALALCLALTTATNPGFVVRITQAGLDYANQQGIAILEKELAQLKLPDISGKSGKVHYDLSRLRLPNFRLPYSRITPVSNVGLQVSISKASAELDGNCRVKFLLIRSSGSFNLKVENVSIKIILRLGSDITGKPTISTSDCSASISKVRVLFSGKLGWLYNLFHKTIESRLRKNFESEVCDSVAKSVQNKLQKQILTLPVTVKVDNKTGIDYSLVAPPRATAQYLDLDLKGEFYSLAKRFTVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYQKAGALVFEITEAMIPKEAGFRLDTSVFSAFIPQLEEMYPNMPMKFRLSAPTAPFLTIGPGGISFQPIVDAQAYAILPNSSLVPLFLLSLTIESRACMSPVLQAKAFLPSLPTSQVRVMQSIMNVLTSRVVLPRVNARLHEGWHLPIPNGVQLSNVLVKFHQNFLLLGADLHM
    

Molecular Weight50196.07 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)15.08

Net Charge (pH 7.4) 14.33

Charge Density (pH 7.0) 0.0329

GRAVY Index0.20

Hydrophobic Moment 0.75

Boman Index0.14

Instability Index42.95

Aliphatic Index 104.96

Aromaticity 0.0852

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29255.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283662 VERIFIED: NO

Provenance & Taxonomy

OrganismFicedula albicollis [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence