Peptide Database

Peptide NameS-type Pyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length603 amino acids

Chemical FormulaC2895H4511N783O876S17

DescriptionStandard

        MPGAARINDIGSGHDCFPETPITEGSTNVIINGQPAARKGDAVLLHDCPCPSTSHGIHSRKIAEGSSSVIINGKPAARIGDSISCGGVIISGSGNVIIGDTPYKSPVQDCAKQAALSRAPLLALTPMLTVPPVYAKSCLQDKSYIRAKTEKEPVKNFGDMVLFAQPEQDDCCGYGHHTADNPHEVVQYAQAAKKKTTVSETAISSPKYSSPKRPQLEPWYKTLFDLLTATDDKPLSQAPVAKSLTGPVVAEKQKEPVASADVGLLAATGVMTQVWGEWSLGGVLSAARGVPYIGALASALYIPSAGEGSDKVPGQNEHWLEDELRQKGWAGETATTRVRFFWRPDIHGNMQVYGVHTGEGTPYEGVRVANMVWDPNIQGYSFTPSPGVDAPTITWTPEKPEGAEPISHTGSPVKPIDQPTILIYPIPEDETETTTPPFPVPDAHDFNDWILVFPDGSEIKPIYVYLQSVRDKPGTVTGKGEVLSGEGKWLEAASSGLGAPVPVQIADKLRGQKFERFDDFREAFWLAVAECPELMEPFSPANKALIKKGRSPYAVPKEQSGGRVVFEIHHKIRIVDGGGVYDIDNMSIATPRRHIVIHSKGAS
    

Molecular Weight64845.61 Da

Isoelectric Point (pI)5.78

Net Charge (pH 7.0)-11.11

Net Charge (pH 7.4) -12.43

Charge Density (pH 7.0) -0.0184

GRAVY Index-0.32

Hydrophobic Moment 0.70

Boman Index0.06

Instability Index42.66

Aliphatic Index 77.48

Aromaticity 0.0730

Extinction Coeff. Reduced 85830.00

Extinction Coeff. Oxidized 86330.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333227 VERIFIED: YES

Provenance & Taxonomy

OrganismPectobacterium polaris [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)