Peptide Database

Peptide NameEnkephalin analog

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC31H47N11O11

DescriptionStandard

        PRPHED
    

Molecular Weight749.77 Da

Isoelectric Point (pI)5.46

Net Charge (pH 7.0)-0.95

Net Charge (pH 7.4) -1.06

Charge Density (pH 7.0) -0.1579

GRAVY Index-2.98

Hydrophobic Moment 0.54

Boman Index-0.72

Instability Index59.97

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 351.22

LogP -3.68

H-bond Donors 12.0

H-bond Acceptors 11.0

Rotatable Bonds 21.0

Heavy Atoms 53.0

Ring Count 3.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0284162 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyEnkephalin

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermHydroxylation

Other ModsPara bromination of amino group of phenylalanine

Bio-Activity Profile

Function

Analgesic

MethodHPLC , reverse phase HPLC, Partition coefficient

Half-LifeMouse plasma, in vitro; >18000 s