Peptide Database

Peptide NameBeta-defensin 50 (BD-50) (mBD-50) (Defensin; beta 37) (Defensin; beta 50) (Prostate beta-defensin 1)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC352H568N92O97S13

DescriptionStandard

        MKTLCFLLLTSGLLYLMVKGVGSHPGTFHVRIKCMPKMTAVFGDNCSFYSSMGDLCNNTKSVCCMVPVRMDNI
    

Molecular Weight8057.68 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)3.61

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0495

GRAVY Index0.45

Hydrophobic Moment 0.41

Boman Index0.19

Instability Index41.98

Aliphatic Index 82.60

Aromaticity 0.0822

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2990.66

LogP -27.71

H-bond Donors 110.0

H-bond Acceptors 116.0

Rotatable Bonds 265.0

Heavy Atoms 554.0

Ring Count 11.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0373865 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic