Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length149 amino acids

Chemical FormulaC720H1175N213O216S10

DescriptionStandard

        METQRASLCLGRWSLWLLLLGLVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTRRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNEVQGVRGGGLCYCRRRFCVCVGRG
    

Molecular Weight16591.98 Da

Isoelectric Point (pI)8.40

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.06

Charge Density (pH 7.0) 0.0164

GRAVY Index-0.30

Hydrophobic Moment 0.77

Boman Index-0.09

Instability Index40.40

Aliphatic Index 87.58

Aromaticity 0.0537

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6919.39

LogP -72.37

H-bond Donors 249.0

H-bond Acceptors 229.0

Rotatable Bonds 545.0

Heavy Atoms 1159.0

Ring Count 21.0

Amide Bonds 159.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176101 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal