Peptide Database

Peptide NameOcriplasmin

Function Ontology

Hemostasis ▸ Fibrinolytic activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC88H142N26O26S2

DescriptionStandard

        APSFDCGKPQVEPKKCPGR
    

Molecular Weight2044.36 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)1.78

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0935

GRAVY Index-1.10

Hydrophobic Moment 0.25

Boman Index-0.25

Instability Index54.25

Aliphatic Index 20.53

Aromaticity 0.0526

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 829.84

LogP -9.56

H-bond Donors 28.0

H-bond Acceptors 30.0

Rotatable Bonds 63.0

Heavy Atoms 142.0

Ring Count 5.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0306438 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyEnzyme

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme replacement Thrombolytic Fibrinolytic