Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC99H152N26O33S4

DescriptionStandard

        GIVEQCCASVCSLYQLEHYCN
    

Molecular Weight2362.68 Da

Isoelectric Point (pI)4.51

Net Charge (pH 7.0)-2.19

Net Charge (pH 7.4) -2.51

Charge Density (pH 7.0) -0.1042

GRAVY Index0.33

Hydrophobic Moment 0.33

Boman Index0.18

Instability Index24.35

Aliphatic Index 88.10

Aromaticity 0.0952

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 958.79

LogP -10.10

H-bond Donors 36.0

H-bond Acceptors 36.0

Rotatable Bonds 75.0

Heavy Atoms 162.0

Ring Count 3.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0257041 VERIFIED: YES

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyInsulin

Tax ID9685

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0353041 VERIFIED: YES

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyInsulin

Tax ID9685

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour