Peptide Database

Peptide NameLysozyme C (EC 3.2.1.17) (1;4-beta-N-acetylmuramidase C)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC738H1123N199O219S10

DescriptionStandard

        SGKYISWEDSCSYLQLQKYERCELAKALKKGGLADFKGYSLENWICTAFHESGYNTASTNYNPPDKSTDYGIFQINSRWWCNDYKTPRSKNTCNIDCKVLLGDDISPAIKCAKRVVSDPNGMGAWVAWKKYCKGKNLSQWTQGCKL
    

Molecular Weight16607.66 Da

Isoelectric Point (pI)8.91

Net Charge (pH 7.0)6.46

Net Charge (pH 7.4) 6.01

Charge Density (pH 7.0) 0.0442

GRAVY Index-0.68

Hydrophobic Moment 0.70

Boman Index-0.08

Instability Index25.47

Aliphatic Index 59.52

Aromaticity 0.1301

Extinction Coeff. Reduced 51910.00

Extinction Coeff. Oxidized 52410.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6823.24

LogP -70.34

H-bond Donors 246.0

H-bond Acceptors 237.0

Rotatable Bonds 548.0

Heavy Atoms 1166.0

Ring Count 32.0

Amide Bonds 160.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141977 VERIFIED: YES

Provenance & Taxonomy

OrganismBufo gargarizans andrewsi [Animal]

FamilyGlycosyl hydrolase 22

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriolytic enzyme Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Glycosidase Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0403720 VERIFIED: YES