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MYP_090699
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Basic Information
Chem-KVL
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C72H136N22O15
Standard
Sequence
KVLGRLVKVLGRLV
Physicochemical Analysis
1549.99 Da
12.00
3.76
3.55
0.2684
1.03
0.84
0.10
-4.90
194.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
617.46
-2.44
23.0
19.0
55.0
109.0
0.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031274 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa ATCC 27853
32 μg/mL
MIC
PaperSystematic alanine and stapling mutational analysis of antimicrobial peptide Chem-KVL
RECORD: Rec_0033783 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Hemolytic
human RBCs
1928
HC50
PMID34662112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34662112/
RECORD: Rec_0091968 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
4 μM
MIC
PMID34662112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34662112/
RECORD: Rec_0094880 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human RBCs
429
HC50
PMID34662112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34662112/
RECORD: Rec_0110035 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
0.5 μM
MIC
PMID34662112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34662112/
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