Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC472H768N136O143S8

DescriptionStandard

        SYFEQKSKAVQFLSVGLSPNWGTNRFKMDGRCEVECLSFEDKIGGCRAELTPLCCKKKKGRIIKSQAGATGSEKQRSSGCELHAANISGFILLTSNMGIL
    

Molecular Weight10892.49 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)5.50

Net Charge (pH 7.4) 5.12

Charge Density (pH 7.0) 0.0550

GRAVY Index-0.28

Hydrophobic Moment 0.47

Boman Index-0.03

Instability Index36.27

Aliphatic Index 73.20

Aromaticity 0.0700

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4544.91

LogP -52.32

H-bond Donors 165.0

H-bond Acceptors 158.0

Rotatable Bonds 378.0

Heavy Atoms 759.0

Ring Count 11.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046333 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal