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MYP_090628
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Basic Information
Temporin-1DRa
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C75H127N19O17
Standard
Sequence
HFLGTLVNLAKKIL
Physicochemical Analysis
1566.93 Da
10.00
1.85
1.59
0.1318
0.92
0.56
0.34
3.51
167.14
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
585.66
-2.04
20.0
20.0
53.0
111.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0305253 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
70.0 μM
HC50
PaperE. Urban et al. / International Journal of Antimicrobial agents 29 (2007) 317-321. Activities of four frog skin-derived antimicrobial peptides (temporin-1DRa, temporin-1Va and the melittin-related peptides AR-23 and RV-23) against anaerobic bacteria
RECORD: Rec_0305749 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus Sens 8325.4 [
8 μg/mL
MIC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0306096 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus DMS20231 [
64 μg/mL
MIC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0306871 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
S. pseudintermedium S70E2 [
8 μg/mL
MIC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0325004 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
L. salivarius DSM20554 [
64 μg/mL
MIC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
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