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MYP_090628
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Basic Information
Temporin-1DRa
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
14 amino acids
C75H127N19O17
Standard
Sequence
HFLGTLVNLAKKIL
Physicochemical Analysis
1566.93 Da
10.00
1.85
1.59
0.1318
0.92
0.56
0.34
3.51
167.14
0.0714
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
585.66
-2.04
20.0
20.0
53.0
111.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155658 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
S. pseudintermedium E139 [
8 μg/mL
MIC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0157917 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
C-terminal amidation
Bio-Activity Profile
Antimicrobial Antifungal
P. acnes
30 μM
MIC
PaperEvidence from peptidomic analysis of skin secretions that the red-legged frogs, Rana aurora draytonii and Rana aurora aurora, are distinct species.
RECORD: Rec_0160698 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
L. casei Shirota [
64 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0164773 VERIFIED: YES
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
S. pseudintermedium E140 [
32 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0173035 VERIFIED: NO
Provenance & Taxonomy
Rana draytonii [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic
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