Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC732H1157N215O218S7

DescriptionStandard

        MAKVQFTKRQETSQIFVHCSATKATMDIGVREIRQWHKEQGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGQPEANFTPQQMSALKGLLHELKGTYPKAVIMAHHDVASKACPSFDLQRWVKTGELVTSDRG
    

Molecular Weight16681.78 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.40

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index39.70

Aliphatic Index 73.58

Aromaticity 0.0728

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6981.65

LogP -74.48

H-bond Donors 246.0

H-bond Acceptors 235.0

Rotatable Bonds 560.0

Heavy Atoms 1172.0

Ring Count 25.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307028 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage 066027 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic