‹ ›
MYP_090615
← PREVIOUS NEXT → BACK
Basic Information
M2 MH
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-H1N1
Enzyme modulation ▸ Enzyme inhibition ▸ Infection inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C123H199N35O20
Standard
Sequence
RKFFKKIYRFFRKLLKRL
Physicochemical Analysis
2488.12 Da
12.00
8.75
8.54
0.4863
-0.65
1.05
-0.45
-4.34
86.67
0.2778
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
955.95
-1.56
37.0
29.0
89.0
178.0
5.0
17.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0011698 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-H3N2 Infection inhibition
H3N2 (A/Sydney/5/97)
0.058 μM
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperEnvelope-deforming antiviral peptide derived from influenza virus M2 protein. | Jung Y, Kong B, Moon S, Yu SH, Chung J, Ban C, Chung WJ, Kim SG, Kweon DH. | Biochem Biophys Res Commun. 2019 Sep 24;517(3):507-512. | DOI:10.1016/j.bbrc.2019.07.088 | PMID:31375212 PMID31375212 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31375212/
RECORD: Rec_0054271 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Infection inhibition
H5N2 (A/aquatic bird/Korea/w81/2005 )
0.066 μM
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperEnvelope-deforming antiviral peptide derived from influenza virus M2 protein. | Jung Y, Kong B, Moon S, Yu SH, Chung J, Ban C, Chung WJ, Kim SG, Kweon DH. | Biochem Biophys Res Commun. 2019 Sep 24;517(3):507-512. | DOI:10.1016/j.bbrc.2019.07.088 | PMID:31375212 PMID31375212 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31375212/
RECORD: Rec_0102326 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-H1N1 Infection inhibition
H1N1 (A/Puerto Rico/8/34)
0.053 μM
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperEnvelope-deforming antiviral peptide derived from influenza virus M2 protein. | Jung Y, Kong B, Moon S, Yu SH, Chung J, Ban C, Chung WJ, Kim SG, Kweon DH. | Biochem Biophys Res Commun. 2019 Sep 24;517(3):507-512. | DOI:10.1016/j.bbrc.2019.07.088 | PMID:31375212 PMID31375212 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31375212/
RECORD: Rec_0195527 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
H5N2(A/aquatic bird/Korea/w81/2005 ):inhibition of infection in Madin-Darby canine kidney epithelial(MDCK) cells
0.066 μM
IC50
PMID31375212 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31375212/
RECORD: Rec_0210020 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-H1N1 Infection inhibition
H1N1 (A/Swine/Iowa/15/30)
0.053 μM
IC50
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperEnvelope-deforming antiviral peptide derived from influenza virus M2 protein. | Jung Y, Kong B, Moon S, Yu SH, Chung J, Ban C, Chung WJ, Kim SG, Kweon DH. | Biochem Biophys Res Commun. 2019 Sep 24;517(3):507-512. | DOI:10.1016/j.bbrc.2019.07.088 | PMID:31375212 PMID31375212 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31375212/
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3