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MYP_090613
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Basic Information
c7
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KKXWKK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0057391 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=p-CF3-Bzl-
Bio-Activity Profile
Antimicrobial Anticancer
Ramos
16±5 μM
IC50
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
RECORD: Rec_0091195 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=p-CF3-Bzl-
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
RECORD: Rec_0110374 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=2-Nal-CH2-
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human red blood cells
256 μM
EC50
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
RECORD: Rec_0141667 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=2-Nal-CH2-
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MRC-5
1030±21 μM
IC50
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
RECORD: Rec_0233371 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lactam
Lactam
X=p-CF3-Bzl-
Bio-Activity Profile
Antimicrobial Anticancer
Ramos
157±30 μM
IC50
PaperPubMed PMID: 22933412 PMID22933412 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22933412/
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