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MYP_090611
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Basic Information
Vitri E
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
29 amino acids
C121H187N35O39S6
Standard
Sequence
GLPVCGETCVGGTCNTPGCSCSWPVCFRN
Physicochemical Analysis
2948.38 Da
5.96
-0.30
-0.59
-0.0102
0.27
0.29
0.19
35.35
43.45
0.0690
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1154.07
-16.79
45.0
45.0
85.0
201.0
6.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012186 VERIFIED: YES
Provenance & Taxonomy
Viola tricolor [Plant]
Cyclotide
214053
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Anticancer Cytotoxic Enzymatic-degradation Antimicrobial
Human glioblastoma U251-MG
54.39 μg/mL
IC50
PaperPeptidomics of Circular Cysteine-Rich Plant Peptides: Analysis of the Diversity of Cyclotides from Viola tricolor by Transcriptome and Proteome Mining | PubMed PMID 20580650 PMID20580650;26399495 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20580650/
RECORD: Rec_0159968 VERIFIED: YES
Provenance & Taxonomy
Viola tricolor [Plant]
Cyclotide
214053
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Anticancer Cytotoxic Enzymatic-degradation Antimicrobial
Human breast adenocarcinoma MDA-MB-231
10 μg/mL
IC50
PaperPeptidomics of Circular Cysteine-Rich Plant Peptides: Analysis of the Diversity of Cyclotides from Viola tricolor by Transcriptome and Proteome Mining | PubMed PMID 20580650 PMID20580650;26399495 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20580650/
RECORD: Rec_0172830 VERIFIED: YES
Provenance & Taxonomy
Viola tricolor [Plant]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 20580652 PMID20580652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20580652/
RECORD: Rec_0211529 VERIFIED: NO
Provenance & Taxonomy
Viola tricolor [Plant]
Cyclotide
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
5-19, 9-21, 14-26
Bio-Activity Profile
Antimicrobial Antitumor
RECORD: Rec_0213391 VERIFIED: YES
Provenance & Taxonomy
Viola tricolor [Plant]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
BEL-7402
10 μg/mL
IC50
PaperPubMed PMID: 20580652 PMID20580652 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20580652/
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