Peptide Database

Peptide NameUnnamed

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length86 amino acids

Chemical FormulaC439H692N118O135S2

DescriptionStandard

        SQAEFDKAAEDVKHLKTKPADDEMLYIYSHYKQATVGDINTERPGLLDLRGKAKWDAWNQLKGTSKEDAMKAYVNKVEDLKKKYGI
    

Molecular Weight9847.03 Da

Isoelectric Point (pI)7.86

Net Charge (pH 7.0)0.64

Net Charge (pH 7.4) 0.29

Charge Density (pH 7.0) 0.0075

GRAVY Index-0.96

Hydrophobic Moment 0.61

Boman Index-0.18

Instability Index25.37

Aliphatic Index 69.30

Aromaticity 0.0930

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4157.06

LogP -37.37

H-bond Donors 142.0

H-bond Acceptors 140.0

Rotatable Bonds 341.0

Heavy Atoms 694.0

Ring Count 14.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0244698 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0318400 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyACBP

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

Other ModsLys7 Acetylation; Lys18 Acetylation; Tyr28 Phosphotyrosine; Lys54 Acetylation; Lys54 N6-malonyllysine; alternate (By similarity); Lys76 Acetylation

Bio-Activity Profile

Function

Neuropeptide Neuroendocrine peptide

RECORD: Rec_0351761 VERIFIED: YES

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyAcyl-CoA-binding protein

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermAcetylation

Other Mods7:N6-acetyllysine; 7:N6-succinyllysine; 16:N6-succinyllysine; 18:N6-acetyllysine; 28:Phosphotyrosine; 54:N6-(2-hydroxyisobutyryl)lysine; 54:N6-acetyllysine; 54:N6-malonyllysine; 54:N6-succinyllysine; 76:N6-acetyllysine; 76:N6-succinylly

Bio-Activity Profile

Function

ACE inhibitory

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour