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MYP_090536
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C12H19N3O6
Standard
Sequence
GEP
Physicochemical Analysis
301.30 Da
4.05
-1.24
-1.44
-0.4124
-1.83
0.31
-0.05
45.73
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
150.03
-1.63
4.0
5.0
7.0
21.0
1.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029008 VERIFIED: NO
Provenance & Taxonomy
Tricholoma giganteum [Fungus]; Agaricus bisporus [Fungus]
ACE-inhibitory peptide
5341
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory Antioxidant
ACE
3200 μM
IC50
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0037508 VERIFIED: YES
Provenance & Taxonomy
Tricholoma giganteum [Fungus]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
40 μM
IC50
RECORD: Rec_0089820 VERIFIED: YES
Provenance & Taxonomy
Tricholoma giganteum [Fungus]; Agaricus bisporus [Fungus]
ACE-inhibitory peptide
5341
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
3200 μM
IC50
PaperIsolation and characterization of a novel angiotensin I-converting enzyme inhibitory peptide derived from the edible mushroom Tricholoma giganteum. PMID15165718 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15165718/
RECORD: Rec_0134489 VERIFIED: NO
Provenance & Taxonomy
Tricholoma giganteum [Fungus]; Agaricus bisporus [Fungus]
ACE-inhibitory peptide
5341
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
36 mmHg
SBP decrease
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0150823 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0.04 μM
IC50
PaperAngiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. PMID17430180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17430180/
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