Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC274H435N67O83S6

DescriptionStandard

        METEKYLQVVEDEELEQLVGGAGPGWVETLTKDCPWKQPAACVIIMGQKICKKCY
    

Molecular Weight6188.17 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-3.53

Net Charge (pH 7.4) -3.82

Charge Density (pH 7.0) -0.0641

GRAVY Index-0.24

Hydrophobic Moment 0.45

Boman Index0.06

Instability Index50.02

Aliphatic Index 81.45

Aromaticity 0.0727

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2405.26

LogP -17.53

H-bond Donors 83.0

H-bond Acceptors 86.0

Rotatable Bonds 207.0

Heavy Atoms 430.0

Ring Count 9.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0156686 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus cereus Rock3-29 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence