Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Standard StatusStandard

Sequence Length1198 amino acids

Chemical FormulaC5850H9130N1670O1806S31

DescriptionStandard

        MDNWSALFDGQTRYVLDINDSTVKADVLRFRGREALSEPFRWDIEFTSLHANIPPEQVLMKYASLRMRGGKNVHGVVTRLEWLSTSRDQSHYRLTLSSRLTLLGYTRQCAVFQNLSVPEVVEQVLRKHGLEGPDFEFRLERTYPARELITQWRETDLQFIQRILSEVGIYWRTEMDDVHGLDTCILADSQLNYRFDVQLPYSEPSGLFDGAADSVWDVRTWHNIATGTVATRDYNYRTATTPMDATVSVRSDAVTTGVHYRYTAPYRDAGDDTSPEPETESGAFYARIHHERELSRSARIHLFSNTAHLTPGQVLEPQGDVITALKEGVILTLVTFRGARDSRLHVSVWGVPYTERYCFRPAEIPRPLIPGTLPARIESREKNDIYAHLDEQGRYRVRLDFDRDATDPGYGYLWLRMAKPTAGETSGWHTPLTDGTEVAIAYSNGDIDLPYIACALYDSEHPDHVTRDNHTRNVLRTPANNKLRMEDRRGEEHIKLATEYGKSQLNSGHMVDSQGQRRGTGAELRTDEHGVIRAGKGLFVSADAQPKAQGEALDRDAALKEIDRLNQQLQQLEIAAEKAQALKADVDSQIQMFAQRLKPLNEALLMTAPEGMALTSGEDMQLAATKNVAVNAGGDISAGVTGNLTALAGEKLGLFARSGQLSLKSGEGAIDVQAQNASLRLFAEKKLTLSSASDISFAGKKRITLIGGGSYLRLEAGKVEYGTTASYMRKVKRTMAASASAKPAEAVSLPPPATMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVDNFGQMTIFAQPVEDDCCGYGHQHEHADDEVVQHAQSAKKRKPDAGGANAPAPAQATAAPLALGAATGVMTQVWGEWSLTGVLGAARGIPYVGAMMSALYVPSAGEGSDRVPGRDEFWYEEELRQKALTGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSENNRYEFTPAHGADGPLITWTPERPEGSDLPSHTGSDIRPIDQATILVTPIPDGKDEYTTPPFPVPEERDLNDYILVFPADSGIKPIYVYLKDDARNVPGEATGNGVKLSGDKPWLDMSVTNSGEGAPIPSQIADKLRGQKFNSFDDFRETIWNEIGRHPELTKDFTTVNKDRIEDGLAPWVPKEGQYIGPNSIVKKFAIHHVVPIKDGGGVYDMDNLRIVTPKLHDEIHYRR
    

Molecular Weight132745.19 Da

Isoelectric Point (pI)5.61

Net Charge (pH 7.0)-27.56

Net Charge (pH 7.4) -29.84

Charge Density (pH 7.0) -0.0230

GRAVY Index-0.51

Hydrophobic Moment 0.74

Boman Index-0.05

Instability Index33.58

Aliphatic Index 75.68

Aromaticity 0.0801

Extinction Coeff. Reduced 172580.00

Extinction Coeff. Oxidized 173080.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189656 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase

TargetEscherichia coli