Peptide Database

Peptide NameDEFSN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC410H664N122O137S7

DescriptionStandard

        MRTLALLAALLLLALQAQAGPLQERAEEAPKQEQPDTEDQDMAISFAGDESLGVRAAGERPQHCRAGACRFPESVSGSCLSSGEEYPLCCR
    

Molecular Weight9718.85 Da

Isoelectric Point (pI)4.61

Net Charge (pH 7.0)-6.43

Net Charge (pH 7.4) -6.79

Charge Density (pH 7.0) -0.0707

GRAVY Index-0.30

Hydrophobic Moment 0.45

Boman Index-0.04

Instability Index65.70

Aliphatic Index 77.47

Aromaticity 0.0330

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4143.71

LogP -48.68

H-bond Donors 145.0

H-bond Acceptors 139.0

Rotatable Bonds 322.0

Heavy Atoms 676.0

Ring Count 10.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0218502 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence