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MYP_090466
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Basic Information
P2-Hp-1935
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C86H154N26O24
Standard
Sequence
KLSPSLGPVSKGKLLAGQR
Physicochemical Analysis
1936.30 Da
11.26
3.76
3.55
0.1977
-0.28
0.40
-0.04
35.00
102.63
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
813.28
-9.22
28.0
28.0
66.0
136.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0065877 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0120738 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
66 μM
MIC
PaperAntimicrobial Peptides from Skin Secretions of Hypsiboas pulchellus (Anura: Hylidae).
RECORD: Rec_0211668 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0228233 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
33 μM
MIC
RECORD: Rec_0238743 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25929
66 μM
MIC
PMID24717080 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24717080/
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