Peptide Database

Peptide NameLL-37 (6-20)[F1G,K5A,E6K,E11R,F12A], LLAP

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC73H141N29O17

DescriptionStandard

        GRKSAKKIGKRAKRI
    

Molecular Weight1697.08 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.54

Charge Density (pH 7.0) 0.5170

GRAVY Index-1.47

Hydrophobic Moment 0.87

Boman Index-0.69

Instability Index41.48

Aliphatic Index 65.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 806.75

LogP -8.99

H-bond Donors 31.0

H-bond Acceptors 25.0

Rotatable Bonds 66.0

Heavy Atoms 119.0

Ring Count 0.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000579 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

TargetMurine macrophage cells J774A.1 (50% Cell death at 7727 microg/ml

Activity774 μg/mL

MethodHemolysis

RECORD: Rec_0386278 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMycobacterium smegmatis mc2-155

Activity600 μg/mL

MethodMIC