Peptide Database

Peptide Nameholosin 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC177H289N65O46S6

DescriptionStandard

        GFGCPLNQRACHRHCRSIGRRGGFCAGLIKQTCTCYRK
    

Molecular Weight4255.99 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)7.87

Net Charge (pH 7.4) 7.48

Charge Density (pH 7.0) 0.2072

GRAVY Index-0.48

Hydrophobic Moment 0.79

Boman Index-0.22

Instability Index73.80

Aliphatic Index 46.32

Aromaticity 0.0789

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1822.22

LogP -23.20

H-bond Donors 73.0

H-bond Acceptors 62.0

Rotatable Bonds 141.0

Heavy Atoms 294.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333197 VERIFIED: YES

Provenance & Taxonomy

OrganismIxodes holocyclus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetStaphylococcus aureus

Activity8 μM

MethodMIC

RECORD: Rec_0411975 VERIFIED: YES