Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC136H209N35O43

DescriptionStandard

        IEPHDWTKNITDKIDQIIHDFVDKT
    

Molecular Weight3022.32 Da

Isoelectric Point (pI)4.80

Net Charge (pH 7.0)-3.06

Net Charge (pH 7.4) -3.37

Charge Density (pH 7.0) -0.1224

GRAVY Index-0.85

Hydrophobic Moment 0.70

Boman Index-0.09

Instability Index32.16

Aliphatic Index 89.60

Aromaticity 0.0800

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1274.81

LogP -9.77

H-bond Donors 42.0

H-bond Acceptors 42.0

Rotatable Bonds 100.0

Heavy Atoms 214.0

Ring Count 6.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383070 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial

RECORD: Rec_0422725 VERIFIED: YES

Provenance & Taxonomy

OrganismAvian leukosis virus [Virus]

FamilyVirus-derived peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Entry inhibitor Fusion inhibitor

TargetAvian sarcoma and leukosis virus A (Virus entry); QT6

MethodCell-fusion assay

PaperHeptad repeat 2-based peptides inhibit avian sarcoma and leukosis virus subgroup a infection and identify a fusion intermediate. | Netter RC, Amberg SM, Balliet JW, Biscone MJ, Vermeulen A, Earp LJ, White JM, Bates P. | J Virol. 2004 | PMID:15564453 PMID15564453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15564453/