Peptide Database

Peptide NamePuroindoline-B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length148 amino acids

Chemical FormulaC747H1151N207O207S14

DescriptionStandard

        MKTLFLLALLALVASTTFAQYSEVGGWYNEVGGGGGSQQCPQERPKLSSCKDYVMERCFTMKDFPVTWPTKWWKGGCEHEVREKCCKQLSQIAPQCRCDSIRRVIQGRLGGFLGIWRGEVFKQLQRAQSLPSKCNMGADCKFPSGYYW
    

Molecular Weight16792.30 Da

Isoelectric Point (pI)9.06

Net Charge (pH 7.0)7.50

Net Charge (pH 7.4) 7.05

Charge Density (pH 7.0) 0.0507

GRAVY Index-0.36

Hydrophobic Moment 0.63

Boman Index-0.02

Instability Index45.91

Aliphatic Index 62.57

Aromaticity 0.1216

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 41075.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6678.83

LogP -63.02

H-bond Donors 243.0

H-bond Acceptors 230.0

Rotatable Bonds 553.0

Heavy Atoms 1175.0

Ring Count 32.0

Amide Bonds 160.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045542 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0070445 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetA. tumefaciens (Gram-negative)

RECORD: Rec_0195462 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0237841 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetC. michiganensis (Gram-positive)

RECORD: Rec_0338471 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defense peptide Anti-Gram-negative Anti-Gram-positive Toxin Synergistic peptide Non-hemolytic

TargetP. syringae (Gram-negative)