Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length583 amino acids

Chemical FormulaC2694H4275N813O854S8

DescriptionStandard

        MSGGDGIGHNSGAHSTGGVNGSSSGRGGSSSGGGNNPNSGPGWGTTHTPDGHDIHNYNPGEFGGGGHKPGGNGGNHSGGTGDGQPPGAAMAFGFPALVPAGAGGLAVTVSGDALAAAIADVLAVLKGPFKFGAWGIALYGILPTEIAKDDPRMMSKIVTSLPADAVTESPVSSLPLGQATISVTKRVTDVVKDERQHIAVVAGVPASIPVVDAKPTTHPGVFSVSAPGLPDLQVSTVKNAPATTALPRGVTDEKDRTVDPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQDEENRRQQEWDATHPVEVAERNYRLASDELNRANVDVAGKQERQIQAAQAVAARKGELDAANKTFADAKEEIKKFERFAHDPMAGGHRMWQMAGLKAQRAQNEVNQKQAEFNAAEKEKADADAALNVALESRKQKEQKAKDASDKLDKENKRNHPGKATGKGQPVGDKWLEDAGKEAGAPVPDRIADKLRDKEFKNFDDFRKKFWEEVSKDPELIKQLKNQNKTNVQKGKAPFAKKKDQVGGRERFELHHNKPISQDGGVYDMDNIRVTTPKRHIDIHRGK
    

Molecular Weight61973.22 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)3.16

Net Charge (pH 7.4) 1.86

Charge Density (pH 7.0) 0.0054

GRAVY Index-0.72

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index36.50

Aliphatic Index 63.48

Aromaticity 0.0515

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283642 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin/Colicin

Tax ID28901

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0328662 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica subsp. houtenae serovar 44:z36[z38]:- [Bacterium]

FamilyPyocin/Colicin

Tax ID1967609

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0341340 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica subsp. enterica serovar Strasbourg [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Endonuclease Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli

RECORD: Rec_0420812 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enteritidis [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Endonuclease Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli