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MYP_090249
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Basic Information
Brevinin-1HB1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C122H206N28O26S3
Standard
Sequence
FLPAIIGMAAKVLPAFLCKITKKC
Physicochemical Analysis
2577.31 Da
9.70
3.74
3.50
0.1557
1.20
0.48
0.38
39.75
126.25
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
839.35
-1.80
30.0
33.0
84.0
179.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0270577 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
37.5 μM
MIC
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0354169 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae 08040724
75.0 μM
MIC
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0364923 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
Escherichia coli ATCC 25922, Candida albicans ATCC 10231, and C. glabrata 090902
37.5 μM
MIC
PaperIdentification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0375740 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
4.7 μM
MIC
PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
RECORD: Rec_0377973 VERIFIED: YES
Provenance & Taxonomy
Pelophylax hubeiensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
Pseudomonas aeruginosa CGMCC 1.50, Klebsiella pneumoniae 08040724
75 μM
MIC
PaperIdentification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. PMID28402481 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28402481/
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