Peptide Database

Peptide NameDefensin-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC262H434N86O88S7

DescriptionStandard

        EEYEPLEHAGIEERADRQRRVTCDLLSIKGVAEHSACAANCLSMGKAGGRCENGICLCR
    

Molecular Weight6421.23 Da

Isoelectric Point (pI)5.60

Net Charge (pH 7.0)-2.03

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.0344

GRAVY Index-0.42

Hydrophobic Moment 0.52

Boman Index-0.14

Instability Index45.68

Aliphatic Index 74.58

Aromaticity 0.0169

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2826.55

LogP -34.08

H-bond Donors 105.0

H-bond Acceptors 95.0

Rotatable Bonds 220.0

Heavy Atoms 443.0

Ring Count 4.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0058451 VERIFIED: NO

Provenance & Taxonomy

OrganismBombus pascuorum [Animal]

FamilyDefensin

Tax ID65598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal