Peptide Database

Peptide NameHuman SCPPPQ1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC357H544N76O88S

DescriptionStandard

        MLPIPLEQYAESSSEQRFIFYPPQVPPFFPQVLFPLPPQPPLVLTPNDLIALLIAILNQLGILFP
    

Molecular Weight7340.66 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.49

Net Charge (pH 7.4) -3.72

Charge Density (pH 7.0) -0.0537

GRAVY Index0.53

Hydrophobic Moment 0.42

Boman Index0.36

Instability Index82.16

Aliphatic Index 126.00

Aromaticity 0.1231

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2479.86

LogP -7.86

H-bond Donors 73.0

H-bond Acceptors 86.0

Rotatable Bonds 214.0

Heavy Atoms 522.0

Ring Count 22.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0408994 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetPorphyromonas gingivalis

Activity20 μM

MethodMIC