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MYP_090223
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Basic Information
Jingdongin-1-GN1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
17 amino acids
C97H160N20O21S2
Standard
Sequence
FLPLFLPKIICEITKKC
Physicochemical Analysis
2006.56 Da
8.86
1.74
1.50
0.1024
0.96
0.65
0.31
38.41
137.65
0.1176
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
646.93
0.42
23.0
25.0
65.0
140.0
4.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0261974 VERIFIED: YES
Provenance & Taxonomy
Amolops granulosus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Psychrobacter faecalis X29
50 μM
MIC
PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0269082 VERIFIED: YES
Provenance & Taxonomy
Hylarana taipehensis [Animal]
110118
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
E.cloacae CGMCC 1.57
>100 μM
MIC
PaperIdentification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0272684 VERIFIED: YES
Provenance & Taxonomy
Amolops granulosus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecium 091299
PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0298204 VERIFIED: YES
Provenance & Taxonomy
Amolops granulosus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0312019 VERIFIED: YES
Provenance & Taxonomy
Amolops granulosus [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
100 μM
MIC
PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
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