Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC381H616N108O103S9

DescriptionStandard

        SGEFSALRATLILLNCFPTTPPQSGQNIYIRRLLNTCWRMKGVCRTVCKKNEIFHIFCGLHQLCCIDASSMPVLTGK
    

Molecular Weight8646.21 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)5.57

Net Charge (pH 7.4) 5.14

Charge Density (pH 7.0) 0.0723

GRAVY Index0.17

Hydrophobic Moment 0.86

Boman Index0.08

Instability Index57.46

Aliphatic Index 91.17

Aromaticity 0.0779

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3382.78

LogP -32.69

H-bond Donors 125.0

H-bond Acceptors 120.0

Rotatable Bonds 283.0

Heavy Atoms 601.0

Ring Count 13.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0201519 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence