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MYP_090139
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Basic Information
Fengycin B2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
10 amino acids
C58H85N11O20
Standard
Sequence
EKYTEVPEYV
Physicochemical Analysis
1256.36 Da
4.25
-2.16
-2.34
-0.2160
-1.09
0.40
-0.10
56.41
58.00
0.2000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
515.04
-2.42
17.0
18.0
38.0
89.0
3.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0258403 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Gram-negative
PaperPubMed PMID: 24312083 | PubMed PMID: 22847390 PMID24312083;22847390 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24312083/
RECORD: Rec_0258932 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0284847 VERIFIED: NO
Provenance & Taxonomy
Bacteria [Bacterium]
2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0304433 VERIFIED: YES
Provenance & Taxonomy
Bacillus subtilis [Bacterium]
1423
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Lipidation
Esterification
K2 is Orn. The carboxylic group of the C-terminal V forms an ester bond with the side chain of Y3 OH. Also Fengycin B2 was found by Roy et al. 2013 and it is exactly the same as Fengycin
Bio-Activity Profile
Antifungal
Staphylococcus epidermidis
1000 μg/mL
MIC
PaperLipopeptides from the banyan endophyte, Bacillus subtilis K1: mass spectrometric characterization of a library of fengycins.
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