Peptide Database

Peptide NameSLAY-screened peptide P402

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC33H47N13O13

DescriptionStandard

        PDHNNHT
    

Molecular Weight833.81 Da

Isoelectric Point (pI)5.99

Net Charge (pH 7.0)-0.87

Net Charge (pH 7.4) -1.02

Charge Density (pH 7.0) -0.1237

GRAVY Index-2.74

Hydrophobic Moment 0.11

Boman Index-0.46

Instability Index20.86

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 425.00

LogP -6.73

H-bond Donors 14.0

H-bond Acceptors 14.0

Rotatable Bonds 24.0

Heavy Atoms 59.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170515 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/