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MYP_090104
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Basic Information
Temporin-ALg
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C94H141N17O17
Standard
Sequence
FFPIVGKLLFGLFGLL
Physicochemical Analysis
1781.23 Da
8.75
0.76
0.55
0.0474
2.01
0.35
0.79
0.19
164.38
0.2500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
517.05
3.10
17.0
18.0
55.0
128.0
5.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009837 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0028209 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
1.25 μg/mL
MIC
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0043547 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus dysenteriae
10.00 μg/mL
MIC
PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
RECORD: Rec_0059687 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0061645 VERIFIED: YES
Provenance & Taxonomy
Amolops loloensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC25922
5 μg/mL
MIC
PaperFive novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis. Comp Biochem Physiol B Biochem Mol Biol. 2010 Jan;155(1):72-76. doi: 10.1016/j.cbpb.2009.10.003. PMID: 19843479. PMID19843479 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19843479/
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