MYP_090070
Emericellipsin B
Antimicrobial
▸
Antifungal
Standard
9 amino acids
C33H56N10O12
Standard
PQAAIAASG
784.86 Da
5.96
-0.04
-0.10
-0.0046
0.60
0.04
0.38
30.29
87.78
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
345.45
-5.28
12.0
12.0
23.0
55.0
1.0
9.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0154019
VERIFIED: YES
Provenance & Taxonomy
Emericellopsis alkaline [Fungus]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
the amino acid sequence has been extensively modified. Structure is Methyldecanoyl-MePro-AHMOD-Ala-Aib-Ile-Aib-bAla-Alaol-Glyol (see below). Chemical modification: P1 is methylated, residue 2 is represented by Q but it is 2-Amino-4-methyl-6-hydroxy-8-oxo decanoic acid (AHMOD), residue 4 is a methylated Ala (Aib), residue 6 is alpha-aminoisobutiric acid, residue 7 is beta-alanine, residue 8 is alaninol, and residue 9 is ethanolamine
Bio-Activity Profile
Antifungal
A. terreus 3 K
4 μg/mL
MIC
RECORD: Rec_0166102
VERIFIED: YES
Provenance & Taxonomy
Emericellopsis alkaline [Fungus]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
the amino acid sequence has been extensively modified. Structure is Methyldecanoyl-MePro-AHMOD-Ala-Aib-Ile-Aib-bAla-Alaol-Glyol (see below). Chemical modification: P1 is methylated, residue 2 is represented by Q but it is 2-Amino-4-methyl-6-hydroxy-8-oxo decanoic acid (AHMOD), residue 4 is a methylated Ala (Aib), residue 6 is alpha-aminoisobutiric acid, residue 7 is beta-alanine, residue 8 is alaninol, and residue 9 is ethanolamine
Bio-Activity Profile
Antifungal
A. fumigatus VKM F-37
8 μg/mL
MIC
RECORD: Rec_0168672
VERIFIED: YES
Provenance & Taxonomy
Emericellopsis alkaline [Fungus]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
the amino acid sequence has been extensively modified. Structure is Methyldecanoyl-MePro-AHMOD-Ala-Aib-Ile-Aib-bAla-Alaol-Glyol (see below). Chemical modification: P1 is methylated, residue 2 is represented by Q but it is 2-Amino-4-methyl-6-hydroxy-8-oxo decanoic acid (AHMOD), residue 4 is a methylated Ala (Aib), residue 6 is alpha-aminoisobutiric acid, residue 7 is beta-alanine, residue 8 is alaninol, and residue 9 is ethanolamine
Bio-Activity Profile
Antifungal
but not other fungi. Microdilution assays: The MIC values for EmiB were in the 4-8 ug/mL range: A. niger ATCC 16404
8 μg/mL
MIC
RECORD: Rec_0206461
VERIFIED: YES
Provenance & Taxonomy
Emericellopsis alkaline [Fungus]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
the amino acid sequence has been extensively modified. Structure is Methyldecanoyl-MePro-AHMOD-Ala-Aib-Ile-Aib-bAla-Alaol-Glyol (see below). Chemical modification: P1 is methylated, residue 2 is represented by Q but it is 2-Amino-4-methyl-6-hydroxy-8-oxo decanoic acid (AHMOD), residue 4 is a methylated Ala (Aib), residue 6 is alpha-aminoisobutiric acid, residue 7 is beta-alanine, residue 8 is alaninol, and residue 9 is ethanolamine
Bio-Activity Profile
Antifungal
A. niger 1133 m
8 μg/mL
MIC
RECORD: Rec_0233321
VERIFIED: YES
Provenance & Taxonomy
Emericellopsis alkaline [Fungus]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
the amino acid sequence has been extensively modified. Structure is Methyldecanoyl-MePro-AHMOD-Ala-Aib-Ile-Aib-bAla-Alaol-Glyol (see below). Chemical modification: P1 is methylated, residue 2 is represented by Q but it is 2-Amino-4-methyl-6-hydroxy-8-oxo decanoic acid (AHMOD), residue 4 is a methylated Ala (Aib), residue 6 is alpha-aminoisobutiric acid, residue 7 is beta-alanine, residue 8 is alaninol, and residue 9 is ethanolamine
Bio-Activity Profile
Antifungal
A. fumigatus 390 m
8 μg/mL
MIC
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