Peptide Database

Peptide NameDefensin; alpha; 27

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC439H731N135O144S8

DescriptionStandard

        MKTLVLLSALALLASQVQADPIQNRDEESKIDEQPGKEDQAVSVSFGDPEGSSLQEESLRDLICYCRTRGCKRRERLNGTCRKGHLMYTLCCR
    

Molecular Weight10460.84 Da

Isoelectric Point (pI)6.56

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.83

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.57

Hydrophobic Moment 0.58

Boman Index-0.19

Instability Index44.31

Aliphatic Index 80.75

Aromaticity 0.0323

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4580.17

LogP -53.50

H-bond Donors 166.0

H-bond Acceptors 153.0

Rotatable Bonds 362.0

Heavy Atoms 726.0

Ring Count 7.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0366257 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic