Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length220 amino acids

Chemical FormulaC1117H1693N253O336S8

DescriptionStandard

        IDDWAEVDYSLNSLPAVFRPFIDLDLKGIVYPAGNYTGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYSAGAFNITIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEVPIISLEQDSFTVEIQGSMEVFAVLPDSATQSLFTMNITANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGVFEISLLENILSYILQTEVIPSANGK
    

Molecular Weight24298.40 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-16.14

Net Charge (pH 7.4) -16.48

Charge Density (pH 7.0) -0.0734

GRAVY Index0.33

Hydrophobic Moment 0.60

Boman Index0.26

Instability Index46.16

Aliphatic Index 99.32

Aromaticity 0.1318

Extinction Coeff. Reduced 23380.00

Extinction Coeff. Oxidized 23505.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172627 VERIFIED: NO

Provenance & Taxonomy

OrganismRhynochetos jubatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria