Peptide Database

Peptide NameMolt-inhibiting hormone

Function Ontology

Developmental biology ▸ Molting regulation

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC396H621N113O118S7

DescriptionStandard

        RVINDDCPNLIGNRDLYKKVEWICDDCANIYRSTGMASLCRKDCFFNEDFLWCVRATERSEDLAQLKQWVTILGAGRI
    

Molecular Weight9077.31 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0165

GRAVY Index-0.28

Hydrophobic Moment 0.61

Boman Index-0.08

Instability Index38.06

Aliphatic Index 86.28

Aromaticity 0.1026

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3791.05

LogP -35.15

H-bond Donors 139.0

H-bond Acceptors 124.0

Rotatable Bonds 303.0

Heavy Atoms 634.0

Ring Count 12.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0344523 VERIFIED: YES

Provenance & Taxonomy

OrganismCallinectes sapidus [Animal]

FamilyMolt-inhibiting hormone

Tax ID6763

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-44; 24-40; 27-53

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Molting regulator

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min

RECORD: Rec_0373766 VERIFIED: NO

Provenance & Taxonomy

OrganismCallinectes sapidus [Animal]

FamilyArthropod CHH/MIH/GIH/VIH hormone

Tax ID6763

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Arthropod neurohormone

RECORD: Rec_0378119 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/