Peptide Database

Peptide NameRecombinant Pro-Omhep1, Recombinant Hepcidin

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC404H629N133O121S15

DescriptionStandard

        MGSSHHHHHHSSGLVPRGSHMIPVNGVTELEEAASNDTPVAARHEMSMQSWMMPNHIREKRQSHLSMCSVCCNCCKNYKGCGFCCRF
    

Molecular Weight9766.11 Da

Isoelectric Point (pI)8.19

Net Charge (pH 7.0)2.30

Net Charge (pH 7.4) 1.45

Charge Density (pH 7.0) 0.0265

GRAVY Index-0.52

Hydrophobic Moment 0.42

Boman Index-0.07

Instability Index53.96

Aliphatic Index 43.68

Aromaticity 0.0460

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4029.56

LogP -50.89

H-bond Donors 148.0

H-bond Acceptors 148.0

Rotatable Bonds 319.0

Heavy Atoms 673.0

Ring Count 19.0

Amide Bonds 93.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417103 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHepcidin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetStaphylococcus aureus CGMCC 1.0363

Activity1.5-3 μM

MethodMIC

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