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MYP_089993
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Basic Information
Recombinant Pro-Omhep1, Recombinant Hepcidin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
87 amino acids
C404H629N133O121S15
Standard
Sequence
MGSSHHHHHHSSGLVPRGSHMIPVNGVTELEEAASNDTPVAARHEMSMQSWMMPNHIREKRQSHLSMCSVCCNCCKNYKGCGFCCRF
Physicochemical Analysis
9766.11 Da
8.19
2.30
1.45
0.0265
-0.52
0.42
-0.07
53.96
43.68
0.0460
6990.00
7490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
4029.56
-50.89
148.0
148.0
319.0
673.0
19.0
93.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007857 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hepcidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2[40-50% Killing = 5 microM]
PMID22051539 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22051539/
RECORD: Rec_0027795 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hepcidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Corynebacterium glutamicum CGMCC 1.1886
03-6 μM
MIC
PMID22051539 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22051539/
RECORD: Rec_0077224 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Hepcidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID22051539 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22051539/
RECORD: Rec_0165894 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hepcidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio parahaemolyticus CGMCC 1.1615
48 μM
MIC
PMID22051539 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22051539/
RECORD: Rec_0168397 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Hepcidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio alginolyticus CGMCC 1.1833
48 μM
MIC
PMID22051539 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22051539/
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