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MYP_089899
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Basic Information
D-VIH-D-sh-Buforin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C107H182N38O22
Standard
Sequence
VIHRAGLQFPVGRVHRLLRK
Physicochemical Analysis
2352.83 Da
12.00
4.91
4.59
0.2454
-0.06
0.81
-0.13
52.84
126.50
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
981.50
-6.83
36.0
29.0
78.0
167.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0328237 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis H37Rv
20 μM
MBC
PMID25891844;30141623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25891844/
RECORD: Rec_0328886 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (5.9+-0.8% Hemolysis at 64 microM, Human embryonic kidney HEK293 cells ( at NA , Human erythrocytes (7.4+-0.7% Hemolysis at 64 microM, Human erythrocytes (6.6+-0.9% Hemolysis at 2 microM, Human erythrocytes (5.3+-1.0% Hemolysis at 2 microM, Human embryonic kidney HEK293 cells (10% Killing at 128 microM
64 μM
Hemolysis
PMID25891844;30141623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25891844/
RECORD: Rec_0329379 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human acute monocytic leukemia THP-1
PMID25891844;30141623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25891844/
RECORD: Rec_0330416 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli DL7
8 μM
MIC
PMID25891844;30141623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25891844/
RECORD: Rec_0331417 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
32
MIC
PMID24803240 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24803240/
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