Peptide Database

Peptide Namebeta-Defensin, EP2D/E

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC189H300N60O59S7

DescriptionStandard

        TICRMQQGICRLFFCHSGEKKRDICSDPWNRCCVSNTDE
    

Molecular Weight4581.23 Da

Isoelectric Point (pI)7.52

Net Charge (pH 7.0)0.44

Net Charge (pH 7.4) 0.10

Charge Density (pH 7.0) 0.0112

GRAVY Index-0.61

Hydrophobic Moment 0.74

Boman Index-0.22

Instability Index23.67

Aliphatic Index 47.44

Aromaticity 0.0769

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1964.45

LogP -23.58

H-bond Donors 75.0

H-bond Acceptors 68.0

Rotatable Bonds 153.0

Heavy Atoms 315.0

Ring Count 6.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141166 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-32; 10-25; 14-33

Bio-Activity Profile

Function

Antimicrobial